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trpB [2017-8-11 16:2:51]
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trpB [2017-8-11 16:2:51]

tryptophan synthase (beta subunit)
Locus
BSU22640
Isoelectric point
5.53
Molecular weight
43.42 kDa
Protein length
400 aa Sequence Blast
Gene length
1200 bp Sequence Blast
Function
biosynthesis of tryptophan
Product
tryptophan synthase (beta subunit)
Essential
no
E.C.
4.2.1.20
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
2,372,304 → 2,373,506

The protein

Catalyzed reaction/ biological activity

  • L-serine 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan glyceraldehyde 3-phosphate H2O (according to Swiss-Prot)
  • Structure

  • 4NEG (from Bacillus anthracis, 60% identity)
  • Expression and Regulation

    Operons

    Description

    Regulatory mechanism

  • MtrB: termination/antitermination, PubMed, in MtrB regulon
  • Regulation

  • not expressed if tryptophan is available (MtrB) PubMed
  • the mRNA is substantially stabilized upon depletion of RNase Y PubMed
  • the RNA switch RNA is degraded by RNase Y PubMed
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    Description

    Regulatory mechanism

  • MtrB: termination/antitermination, PubMed, in MtrB regulon
  • Regulation

  • not expressed if tryptophan is available (MtrB) PubMed
  • the mRNA is substantially stabilized upon depletion of RNase Y PubMed
  • view in new tab

    References

    Reviews

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    Original publications

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